姓名：王茗莹

性别：女

籍贯：山东省安丘市

联系电话：18609881870

E-Mail：18609881870@163.com

职称/职务：无

通讯地址：辽宁省本溪高新技术产业开发区华佗大街26号，沈阳药科大学，邮编117004

办公地点：制药楼236

教育经历：

2020/08-2023/06，沈阳药科大学，中药学院，天然药物化学专业，博士；

2017/09-2020/06，沈阳药科大学，中药学院，药学专业，硕士；

2013/09- 2017/07，沈阳药科大学，药学院，药学专业，学士。

工作经历：

2024/07-至今，沈阳药科大学，制药工程学院药物化学系，教师；

学科/研究方向：天然产物结构修饰及活性评价

科研/获奖情况：

教学/指导研究生情况：有机化学实验

发表论文/出版著作：

代表性论文：

1．Mingying Wang^#, Haonan Li^#, Weiwei Liu^#, et al, Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification, Eur. J. Med. Chem. 2020, 189: 112087. (IF = 6.514)

2．Mingying Wang^#, He Li^#, Fanxing Xu^#, et al, Diterpenoid lead stevioside and its hydrolysis products steviol and isosteviol: Biological activity and structural modification, Eur. J. Med. Chem. 2018, 156: 885-906. (IF = 4.833)

3．Mingying Wang, Xiaoyuan Chen, Ying Qu, et al, Design and synthesis of brefeldin A-isothiocyanate derivatives with selectivity and their potential for cervical cancer therapy, Molecules 2023, 28(11): 4284. (IF = 4.2)

4．Mingying Wang, Baojia Sun, Tao Ye, et al, 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione derivatives of brefeldin A: Design, synthesis and cytotoxicity in MDA-MB-231 human breast cancer cells, Bioorg. Med. Chem. 2023, 90: 117380. (IF = 3.3)

5．Jian Qiao, Mingying Wang, Menghan Cui, et al, Small-molecule probes for fluorescent detection of cellular hypoxia-related nitroreductase, J. Pharmaceut. Biomed. 2021, 203: 114199. (IF = 3.571)

6．Tong Han, Yan Wang, Mingying Wang, et al, Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway, Eur. J. Med. Chem. 2018, 158: 493-501. (IF = 4.833)

7．Xiang Gao, Jia Li, Mingying Wang, et al, Novel enmein-type diterpenoid hybrids coupled with nitrogen mustards: Synthesis of promising candidates for anticancer therapeutics, Eur. J. Med. Chem. 2018, 146: 588-598. (IF = 4.833)

8．Haonan Li, Baojia Sun, Mingying Wang, et al, Bioactive enmein-type 6,7-seco-ent-kaurane diterpenoids: Natural products, synthetic derivatives and apoptosis related mechanism, Arch. Pharm. Res. 2018, 41: 1051-1061. (IF = 2.458)