姓名:胡壮
性别:男
出生年月:1991.01
籍贯:辽宁省锦州市
联系电话:13516084582
E-Mail:huzhuang135@126.com
职称/职务:讲师
通讯地址:辽宁省本溪高新技术产业开发区华佗大街26号,邮编117004
办公地点:办公室制药楼235室
教育经历:
2023年3月毕业于东北大学,高分子化学与物理专业,博士学位
2017年3月毕业于沈阳化工大学,有机化学专业,硕士学位
2014年7月毕业于沈阳化工大学,材料物理专业,学士学位
工作经历:
2023年11月-至今,沈阳药科大学,制药工程学院有机化学教研室;主要讲授《有机化学》、《有机化学实验》、《金属有机化学》等课程。
科研方向:生物医用高分子。
主要从事生物医用高分子材料的合成与药物载体制备,主要进行聚氨基酸类载药纳米胶束的制备和液晶响应型纳米递药系统的构建及其增效癌症化疗机制研究,旨在使药物载体具备良好的生物相容性和抗肿瘤效果,以扩大其在生物医学尤其是药物缓释领域的应用。
部分代表性论文:
1. Zhuang Hu, Gongshu Wang, Shengyun Zhao, etal. Sustained release properties of liquid crystal functionalized poly (amino acid)s nanoparticles. Journal of Molecular Liquids. 2023, 369, 120891.
2. Zhuang Hu, Gongshu Wang, Rui Zhang, etal. Construction of poly(amino acid)s nano-delivery system and sustained release with redox-responsive. Colloids and Surfaces B: Biointerfaces. 2023, 224, 113232.
3. Zhuang Hu, Rui Zhang, Shiying Xu, etal. Construction of nano-drug delivery and antitumor system of stimuli-responsive polypeptides. Colloids and Surfaces B: Biointerfaces. 2023, 226 113310.
4. Zhuang Hu, Gongshu Wang, Rui Zhang, etal. Sustained-release behavior and the antitumor effect of charge-convertible poly(amino acid)s drug-loaded nanoparticles. Drug Delivery and Translational Research. 2023, 13, 2394-2406.
5. Zhuang Hu, Siyu Han, Nan Nie, etal. Preparation and drug release behavior of amphiphilic polyamino acids nanomicelles. Journal of Drug Delivery Science and Technology. 2022, 76, 103806.
6. Zhuang Hu, Kaixia An, Jia Wang, etal. Preparation and drug release behavior of tussah silk fibroin composite membrane. Fibers and Polymers. 2020, 21, 252-261.
7. Zhuang Hu, Jiwei Wang, Siyu Han, etal. Self-assembly behavior and sustained drug release properties of amphiphilic poly(amino acid)s. New Journal of Chemistry. 2022, 46, 19888-19899.
8. Zhuang Hu, Siyu Han, Ting Lei, etal. Study on drug delivery properties of triblock poly (amino acid) nanomicells. International Journal of Polymeric Materials and Polymeric Biomaterials. 2024, 73, 333-344.
9. Zhuang Hu, Zhihao Guo, Siyu Han, etal. Preparation and pH/temperature dual drug release behavior of polyamino acid nanomicelles. Polymer Bulletin. 2022, 79, 4685-4699.
Zhuang Hu, Jiwei Wang, Siyu Han, etal. Study on the sustained release properties of drug-loaded nanomicelles with amphiphilic poly(amino acid)s. Polymer-Plastics Technology and Materials. 2023, 62, 839-854.