姓名:杨华丽
性别:女
籍贯:山东烟台
联系电话:18802421610
E-Mail:yanghuali16@126.com
职称/职务:特聘副研究员
通讯地址:辽宁省本溪市高新技术产业开发区华佗大街26号
办公地点:南校区制药楼303室
教育经历:
2016.09-2020.06,沈阳药科大学,制药工程学院,中药学,博士
2014.09-2016.07,沈阳药科大学,制药工程学院,药物化学,硕士
2010.09-2014.06,沈阳药科大学,制药工程学院,制药工程,学士
工作经历:
2020.12 -至今,沈阳药科大学,制药工程学院,特聘副研究员
2020.10-2020.12,沈阳药科大学,制药工程学院,助教
兼职情况:无
学科/研究方向:多靶点抗阿尔茨海默症和抗肿瘤药物的研究、近红外荧光探针在阿尔茨海默症中的应用;
科研/获奖情况:无
教学/指导研究生情况:指导本科药物化学实验课、药物合成反应实验课、化学制药工艺学实验课
代表性著作:无
代表性论文:
(1) Yang Huali#; Wang Xiaobing#; Wang Cheng; Yin Fucheng; Qu Lailiang; Shi Cunjian; Zhao Jinhua; Li Shang; Ji Limei; Peng Wan; Luo Heng; Cheng MaoSheng*; Kong Lingyi*; Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer, European Journal of Medicinal Chemistry, 2021, 210: 113080.
(2) Yang Huali; Fang Siqiang; Tang Yanwei; Wang Cheng; Luo Heng; Qu Lailiang; Zhao Jinhua; Shi Cunjian; Yin Fucheng; Wang Xiaobing*; Kong Lingyi*; A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease, European Journal of Medicinal Chemistry, 2019, 179: 736-743.
(3) Yang Huali; Cai Pei; Liu Qiaohong; Yang Xuelian; Fang Siqiang; Tang Yanwei; Wang Cheng; Wang Xiaobing*; Kong Lingyi*; Design, synthesis, and evaluation of salicylaldimine derivatives as multitarget-directed ligands against Alzheimer's disease, Bioorganic & Medicinal Chemistry, 2017, 25(21): 5917-5928.
(4) Yang Huali; Cai Pei; Liu Qiaohong; Yang Xuelian; Li Fan; Wang Jin; Wu Jiajia; Wang Xiaobing; Kong Lingyi*; Design, synthesis and evaluation of coumarin-pargyline hybrids as novel dual inhibitors of monoamine oxidases and amyloid-β aggregation for the treatment of Alzheimer's disease,European Journal of Medicinal Chemistry, 2017, 138: 715-728.