姓名:丁怀伟
性别:男
籍贯:山东泰安
联系电话:18341443629
E-Mail:dinghuaiwei627@163.com
职称/职务:副教授
通讯地址:沈阳药科大学南校区24号信箱
办公地点:沈阳药科大学制药楼327
教育经历:博士研究生
工作经历: 2012至今,沈阳药科大学
兼职情况:无
学科/研究方向:药物化学/基于靶点的小分子化合物的设计与合成
科研/获奖情况: 无
教学/指导研究生情况: 无机化学/有指导研究生经历
发表论文/出版著作:
代表性著作:
1. 无机化学实验(第2版全国高等医药院校药学类实验教材),参编
代表性论文:
1. Huai-Wei Ding, Cheng-Long Deng, Dan-Dan Li, Dan-Dan Liu,Shao-MengChai, Wei Wang, Yan Zhang, Kai Chen, Xin Li, Jian Wang, Shao-Jiang Song,Hong-Rui Song. Design, synthesis and biological evaluation of novel4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα. European Journalof Medicinal Chemistry, 2018, 146: 460-470. (IF = 4.519)
2. Yan Xiao, Juan Li, Ya-jun Liu, Shuo Wang, Hui Zhang*, and Huai-wei Ding*. Copper(II) Catalyzed C-HAlkoxylation of 2-Phenyl Pyridines with Aliphatic Diols.EuropeanJournal of Organic Chemistry.https://doi.org/10.1002/ejoc.201800104. (IF = 2.834)
3. Yan-HuaFan, Huai-wei Ding*, Dan-Dan Liu, Hong-Rui Song, Yong-Nan Xu, Jian Wang. Novel 4-aminoquinazoline derivatives induce growth inhibition, cellcycle arrest and apoptosis via PI3Kα inhibition. Bioorganic & MedicinalChemistry. 2018, 26(8): 1675-1685.(IF =2.93)
4. Huai-Wei Ding, Bing-ke Song,Cheng-long Deng, Wei Li, Li Niu, Meng-xuan Bai, Hong-rui Song * and Li-juanZhang *. Synthesis andSmo Activity of Some Novel Benzamide Derivatives.[J]. Molecules, 2018, 23(1),85. (IF = 2.861)
5. YanHua Fan,Wei Li, DanDan Liu, MengXuanBai, HongRui Song, YongNan Xu,SangKook Lee, ZhiPeng Zhou, Jian Wang, Huaiwei Ding*.Design, synthesis, and biological evaluationof novel 3-substituted imidazo[1,2-a]pyridine and quinazolin-4(3H)-onederivatives as PI3Kα inhibitors. European Journal of MedicinalChemistry, 2017, 139:95-106.(IF = 4.519)
6. Huai-Wei Ding, Juan Li,Qing-Hui Guo, Yan Xiao*. Research Progress on Transition-Metal-Catalyzed C-HActivation/C-O Coupling Reaction of Arenes. Chinese journal of organic chemistry. 2017, 37:3112-3129. (IF = 1.010)
7.Xiao-fengChen, Chi-yu Sun, Jing-zhou Zhang, Huaiwei Ding*HongruiSong*. Design, synthesis andevaluation of novel tetrahydrothieno[3,2-c]pyridine derivatives as potentsmoothened antagonists, Med.chem.commun, 2016,7 (5) :960-965. (IF = 2.608)
8. Chiyu Sun, Yangsheng Li,Ailong Shi, Jingzhou Zhang, Yafei Li, Mingming Zhao, Lijuan Zhang, HuachuanZheng, Huaiwei Ding*,Hongrui Song*. Synthesis andevaluation of novel N-3-benzimidazole-phenylbisamide derivatives forantiproliferative and hedgehog pathway inhibitory activity. Medicinal Chemistry Communications, 2015,6(6), 1137-1142. (IF = 2.319)
9. Chi-yu Sun, Yang-shengLi, Ai-long Shi, Ya-fei Li, Rui-fang Cao, Huai-weiDing*, Qing-qing Yin, Li-juan Zhang, Hua-chuan Zheng, Hon-grui Song*.Synthesis and antiproliferative activity of novel4-substituted-phenoxyl-benzamide derivatives. Chinese Chemical Letters. 2015, 26(10): 1307-1310. (IF =1.947)