姓名：秦铭泽

性别：男

籍贯：辽宁开原

联系电话：18341400410

E-Mail：qinmingze001@126.com

职称/职务：副教授

通讯地址：沈阳市沈河区文化路103号

办公地点：制药楼217

教育经历：

2009.09-2014.06：沈阳药科大学 博士研究生；

2005.09-2009.07：沈阳药科大学 本科

工作经历：

2018.01至今：沈阳药科大学 副教授；

2015.01-2017.12：沈阳药科大学 讲师；

2014.08-2014.12：沈阳药科大学 助教

兼职情况：无

学科/研究方向：药物化学/基于免疫调控和表观遗传的新药设计

科研/获奖情况：作为项目负责人，主持了国家自然科学基金、辽宁省自然科学基金、中国博士后科学基金第63批面上资助、辽宁省博士启动基金、辽宁省教育厅一般项目、沈阳药科大学科研启动基金各1项。

教学/指导研究生情况： 承担全校各专业《有机化学》、《有机化学实验》教学/指导硕士研究生6人，其中3人已获得硕士学位。

发表论文/出版著作： 在Eur. J. Med. Chem.、Bioorg. Med. Chem.等药物化学领域期刊发表SCI研究论文16篇，其中第一或通讯作者14篇。

代表性著作：无

代表性论文：

[1] Yajing Liu, Di Yang, Zexin Hong, Su Guo, Moyi Liu, Daiying Zuo, Dandan Ge, Mingze Qin^*, Deyu Sun^*. Synthesis and biological evaluation of 4,6-diphenyl-2-(1H-pyrrol-1-yl)nicotinonitrile analogues of crolibulin and combretastatin A-4. Eur. J. Med. Chem., 2018, 146: 185-193. (IF: 4.519)

[2] Mingze Qin, Ye Tian, Xiaoqing Sun, Juanjuan Xia, Ping Gong, Haotian Zhang^*, Yanfang Zhao^*. Novel methyl indolinone-6-carboxylates containing an indole moiety as angiokinase inhibitors. Eur. J. Med. Chem., 2017, 139: 492-502. (IF: 4.519)

[3] Mingze Qin^*, Shuang Yan, Lei Wang, Haotian Zhang, Ye Tian, Yanfang Zhao, Ping Gong^*. Novel 6-Methoxycarbonyl Indolinones Bearing a Pyrrole Mannich Base Moiety as Angiokinase Inhibitors. Bioorg. Med. Chem., 2017, 25, 1778-1786. (IF: 2.923)

[4] Yunlei Hou, Qi Shen, Zefei Li, Shaowei Chen, Yanfang Zhao, Mingze Qin^*, Ping Gong^*. Palladium-catalyzed three-component tandem reaction for one-pot highly stereoselective synthesis of (Z)-α-hydroxymethyl allylic sulfones. Adv. Synth. Catal. 2018, 360 (4): 631-636. (IF: 5.646)

[5] Mingze Qin, Shuang Yan, Lei Wang, Haotian Zhang, Yanfang Zhao, Shasha Wu, Di Wu, Ping Gong^*. Discovery of novel diaryl area derivatives bearing a triazole moiety as potential antitumor agents. Eur. J. Med. Chem., 2016, 115:1-13. (IF: 4.519)

[6] Mingze Qin^*, Lei Wang, Shuang Yan, Junjie Ma, Ye Tian, Yanfang Zhao, and Ping Gong^*. Identification of hydrazone moiety-bearing aminopyrimidines as potent antitumor agents with selective inhibition of gefitinib-resistant H1975 cancer cells. Chinese Chem. Lett., 2017, 28, 991-994. (IF: 1.947)

[7] Mingze Qin, Tingting Wang, Boxuan Xu, Zonghui Ma, Nan Jiang, Hongbo Xie, Ping Gong^*, Yanfang Zhao^*. Novel hydrazone moiety-bearing aminopyrimidines as selective inhibitors of epidermal growth factor receptor T790M mutant. Eur. J. Med. Chem., 2015, 104: 115-126. (IF: 3.902)