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刘明哲 Teacher Profile

 

姓名:刘明哲

性别:

籍贯:辽宁省沈阳市

联系电话:15940120642

E-Mail:prcmzliu@sohu.com

职称/职务:副教授

通讯地址:辽宁省本溪经济技术开发区(石桥子镇)华佗大街26号沈阳药科大学南校区24号信箱

办公地点:沈阳药科大学南校区制药工程学院楼237

教育经历:

2003/4 - 2006/3,东京大学,工学院化学与生物技术专业,博士

2001/4 - 2003/3,东京大学,工学院化学与生物技术专业,硕士                

2000/4 – 2001/3东京大学,工学院化学与生物技术专业,大学院研究生

1998/11 - 2000/3日本国飞鸟学院,日语研修生

1992/9 - 1996/6,天津大学,应用化学系精细化工专业,学士

1992/9 - 1996/6,天津大学,管理系工业管理工程专业,双学士

工作经历:

2011/6 - 至今,沈阳药科大学,制药工程学院有机化学教研室,副教授

2006/4 - 2011/4,日本理化学研究所(RIKEN),合同制研究员

2007/4 - 2010/3日本理化学研究所(RIKEN),基础科学特别研究员

2006/9 - 2007/3,日本学术振兴会(JSPS),特别研究员

1996/7 - 1998/10天津乐金精密化工有限公司,职员

 

兼职情况:

中国药学会会员,中国化学会会员,中国生物材料学会会员,日本化学会会员

日本理化学研究所(RIKEN)客座研究员,Bioorg. Med. Chem. Lett.J. Mater. Chem. B期刊审稿人

学科/研究方向:

药物化学,生物有机化学,生物材料

科研/获奖情况:

1.  刘明哲,赵海旭,蒋刚锋,翁金鹏,A Signal-accumulating DNAzyme-crosslinked hydrogel for colorimetric sensing of hydrogen peroxide辽宁省自然科学学术成果奖(学术论文类),二等奖,2017.09.19

2. 刘明哲,In vitro selection of a photo-responsive peptide aptamer using ribosomedisplay2013年辽宁省自然科学学术成果奖(学术论文类),二等奖,2013.08.02

教学/指导研究生情况:

指导硕士研究生18,其中合作指导2,已毕业7指导本科毕业专题生30名,其中毕业26名。

发表论文/出版著作:

代表性著作:

1. Hara S., Liu Mingzhe, Wang W., Xu M. Y., Li Z., and Ito Y., “Stabilized ribosome display for     in vitro selection”, in “Ribosome Display and Related Display Technologies: Methods and Protocols”, “Methods in Molecular Biology”, ed by Julie Douthwaite and Ron Jackson, Humana Press, Cambridge, p.59-73, (2011)

2. Liu, Mingzhe; Abe, H.; Ito, Y., “Hemin-Binding Aptamers and Aptazymes”, Green Polymer Chemistry: Biocatalysis and Biomaterials, Cheng, H. N.; Gross, R. A., Eds., American Chemical Society: Washington, DC, 2010, 111-123.

3. Ito, Y.; Abe, H.; Wada, A.; Liu, Mingzhe, “Design and synthesis of biorelated polymers by combinatorial bioengineering”, Polymer biocatalysis and biomaterials II, ACS Symp. Ser., 2008, 999 194-215.  

代表性论文:

1. Jiang, G.; Weng, J.; Kong, L.; Xu, H.; Liu Mingzhe* “Reduction-sensitive N,N'-dimethacryloylcystine nanohydrogel for triggered drug release”, Materials Letters, 2017, 189, 122-125. (IF=2.437)

2. Zhao, H.; Jiang, G.; Weng, J.; Ma, Q.; Zhang, H.; Ito, Y. and Liu, Mingzhe* “A Signal-accumulating DNAzyme-crosslinked hydrogel for colorimetric sensing of hydrogen peroxide”, Journal of Materials Chemistry B, 2016, 4, 4648-4651. (IF=4.872)

3. Liu, Mingzhe; Tada, S.; Ito, M.; Abe, H.; Ito, Y.*In vitro selection of a photo-responsive peptide aptamer using ribosome displayChemical Communications, 2012, 48, (97), 11871-11873. (IF=6.567)

4.  Liu, Mingzhe; Xu, M. Y.; Loh, X. J.; Abe, H.; Tsumuraya, T.; Fujii, I.; Li, J.; Son, T. I.; Ito, Y.* PEGylated antibody in organic mediaJournal of Bioscience and Bioengineering, 2011, 111, (5), 564-568. (IF=1.964)

5.  Liu, Mingzhe; Jinmei, H.; Abe, H.; Ito, Y. *In Vitro Selection of a Photoresponsive RNA Aptamer to Hemin, Bioorganic & Medicinal Chemistry Letters, 2010, 20, (9), 2964-2967. (IF=2.486)

6. Liu, Mingzhe; Kagahara, T.; Abe, H.; Ito, Y. * In vitro selection of hemin-binding catalytic RNA, Bioorganic & Medicinal Chemistry Letters, 2009, 19, (5), 1484-1487. (IF=2.486)

7.  Liu, Mingzhe; Kagahara, T.; Abe, H.; Ito, Y. * Direct In Vitro Selection of Hemin-Binding DNA Aptamer with Peroxidase Activity, Bulletin of the Chemical Society of Japan, 2009, 82, (1), 99-104. (IF=1.372)

8.  Liu, Mingzhe; Jinmei, H.; Abe, H.; Ito, Y. * Chemical aminoacylation of RNA by an intermolecular adenosine transfer reaction. Chemistry Letters, 2008, 37, (1), 102-103. (IF=1.55)

9.  Liu, Mingzhe; Asanuma, H. *; Komiyama, M., Azobenzene-tethered T7 promoter for efficient photoregulation of transcription, Journal of the American Chemical Society, 2006, 128, (3), 1009-1015. (IF=13.038)

 

 

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