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刘亚婧 Teacher Profile

 

姓名:刘亚婧

性别:女

籍贯:河北省唐山市

联系电话:13080755980

E-Mail:lyjpharm@126.com

职称/职务:副教授

通讯地址:辽宁省本溪市溪湖区红柳路沈阳药科大学南校区,37#

办公地点:辽宁省本溪市溪湖区红柳路沈阳药科大学南校区制药楼217

教育经历:

1997.9-2001.7 沈阳药科大学 制药工程学院 化学制药专业 学士学位

2002.9-2005.7 沈阳药科大学 制药工程学院 药物化学专业 硕士学位

2005.9-2008.7 沈阳药科大学 制药工程学院 药物化学专业 博士学位

工作经历:

2001.7-2002.9 连云港豪森制药有限公司

2008.9-至今 沈阳药科大学 制药工程学院 药物化学教研室

兼职情况:无

学科/研究方向:药物化学,小分子靶向抗肿瘤药物、抗血栓药物及抗病毒药物的设计、合成及活性研究

科研/获奖情况:

 

教学/指导研究生情况: 主讲《药物化学》药学专业、药学专升本专业,自2014年至今指导硕士研究生毕业6人,在读研究生8人。

发表论文/出版著作: 近五年第一作者或通讯作者发表研究性论文14篇,其中SCI收载10篇。

代表性著作:无

代表性论文:
1. Yajing Liu, Di Yang, Zexin Hong, Su Guo, Moyi Liu, Daiying Zuo, Dandan Ge, Mingze Qin*, Deyu Sun*. Synthesis and biological evaluation of 4,6-diphenyl-2-(1H-pyrrol-1-yl) nicotinonitrile analogues of crolibulin and combretastatin A-4. European Journal of Medicinal Chemistry, 2018, 146: 185-193.

2. Moyi Liu, Qiaoling Xu, Su Guo, Ruixi Zuo, Yue Hong, Yong Luo, Yingxiu Li, Ping Gong, YajingLiu*. Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B. 2018, 26: 2621-2631.

3. Xiaoqing Sun, Zexin Hong, Moyi Liu, Su Guo, Di Yang, Yong Wang, Tian Lan, Linyu Gao, Hongxia Qi, Ping Gong, Yajing Liu*. Design, synthesis, and biological activity of novel tetrahydropyrazolopyridone derivatives as FXa inhibitors with potent anticoagulant activity. Bioorganic & Medicinal Chemistry, 2017 (25): 2800-2810.

4. Yong Wang, Xiaoqing Sun , Di Yang, Zhuang Guo, Xuxu Fan, Minhua Nie , Feng Zhang, Yue Liu, Yue Li, Yulin Wang, Ping Gong, Yajing Liu* . Design, synthesis, and structure–activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element. Bioorganic & Medicinal Chemistry, 2016, 24: 5646–5661.

5. Yajing Liu, Guobing Feng, Zonghui Ma, Chen Xu, Zhuang Guo, Ping Gong*, and Liying Xu*.Synthesis and Anti-Hepatitis B Virus Evaluation of 7-Methoxy-3-heterocyclic quinolin-6-ols.  Arch. Pharm. Chem. Life Sci. 2015, 348, 1–10.

 

 

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