姓名：胡春

性别：男

籍贯：江苏省沭阳县

联系电话：024-43520246

E-Mail：chunhu1999@163.com

职称/职务：教授

通讯地址：辽宁省本溪高新技术产业开发区华佗大街26号

办公地点：制药楼205室

教育经历：

1981.9-1985.7，江苏师范大学化学专业本科生

1985.9-1988.6，东北师范大学有机化学专业硕士生

1993.9-1999.1，沈阳药科大学药物化学专业博士生

工作经历：

1988.7-现在，沈阳药科大学制药工程学院教师

兼职情况：

《中国药物化学杂志》编委、《沈阳药科大学学报》编委、辽宁省化学会理事、辽宁省高等学校化学类专业教学指导委员会委员

学科/研究方向：

靶向药物的研究与开发、药物合成工艺研究、杂环化学研究

科研/获奖情况：

2014年沈阳市科学技术进步二等奖

2015年辽宁省科学技术进步三等奖

教学/指导研究生情况：

近5年来，讲授本科生“有机化学”合计780标准学时，“精细化学品化学”合计160标准学时，“化学信息学基础”合计160标准学时，研究生“化学信息学”合计200标准学时，指导药物化学专业、化学专业、应用化学专业硕士研究生合计44人，指导药物化学专业博士研究生6人。

发表论文/出版著作：

代表性著作：

胡春主编，有机化学，高等教育出版社，2012年

胡春主编，有机化学，第三版，中国医药科技出版社，2021年

代表性论文：

◎Li-Ping Jin, Qian Xie,  Er-Fang Huang, Lin Wang, Bing-Qi Zhang, Jian-Shu Hu, David Chi-Cheong Wan, Zhe Jin, Chun Hu. Design, synthesis, and biological activity of a novel series of benzofuran derivatives against oestrogen receptor-dependent breast cancer cell lines. Bioorganic Chemistry, 2020, 95: 103566.

◎Zhe Jin, Ying Wang, Xiao-Fei Yu, Qi-Qi Tan, Shi-Shao Liang, Tai Li, Hong Zhang, Pang-Chui Shaw, Jian Wang, Chun Hu. Structure-based virtual screening of influenza virus RNA polymerase inhibitors from natural compounds: Molecular dynamics simulation and MM-GBSA calculation. Computational Biology and Chemistry, 2020, 85: 107241.

◎Jian Feng, Tai Li, Shishao Liang, Chuanming Zhang, Xiaoyu Tan, Ning Ding, Xin Wang, Xiaoping Liu, Chun Hu. Synthesis and biological evaluation of a new series of 1-aryl-3-[4-(pyridin-2-ylmethoxy)phenyl]urea derivatives as new anticancer agents. Medicinal Chemistry Research, 2020, 29(8): 1413-1423.

◎Zhe Jin, Chao Zhang, Miao Liu, Simeng Jiao, Jing Zhao, Xiaoping Liu, Huangquan Lin, David Chi-Cheong Wan, Chun Hu. Synthesis, biological activity, molecular docking studies of a novel series of 3-Aryl-7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives as the acetylcholinesterase inhibitors. Journal of Biomolecular Structure and Dynamics, 2021, 39(7): 2478-2489.

◎Dong Cai, Tai Li, Qian Xie, Xiaofei Yu, Wei Xu, Yu Chen, Zhe Jin, Chun Hu. Synthesis, characterization, and biological evaluation of novel 7-oxo-7H-thiazolo[3,2-b]-1,2,4-triazine-2-carboxylic acid derivatives. Molecules, 2020, 25(6): 1307.

◎Chao Zhang, Qian Xie, Chi Cheong Wan, Zhe Jin, Chun Hu. Recent advances in small-molecule HIV-1 integrase inhibitors. Current Medicinal Chemistry, 2021, 28, 4910-4934.

◎Hai-Ming Wang, Chao-Dong Xiong, Xiao-Qu Chen, Chun Hu, Dong-Yu Wang. Preparation of sulfamates and sulfamides using a selective sulfamoylation agent. Organic Letters, 2021, 23: 2595−2599.

◎Shicheng Hou, Shishao Liang, Chao Zhang, Yingmei Han, Jianhui Liang, Hongyu Hu, Xingeng Zhang, Chun Hu, Xiaoping Liu, Hong Zhang. Design, synthesis and anticancer activity of a new series of N-aryl-N'-[4-(pyridin-2-ylmethoxy)benzyl]urea derivatives. Molecules, 2021, 26: 3496.

◎Chao Zhang, Junjie Xiang, Qian Xie, Jing Zhao, Hong Zhang, Erfang Huang, Pangchui Shaw, Xiaoping Liu, Chun Hu. Identification of influenza PAN endonuclease inhibitors via 3D-QSAR modeling and docking-based virtual screening. Molecules, 2021, 26: 7129.

◎Qian Xie, Yanni Shen, Yanli Meng, Jianhui Liang, Jing Xu, Shishao Liang, Xiaoping Liu, Yan Wang, Chun Hu.  Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione derivatives as RAF-MEK-ERK pathway signaling pathway blockers: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships. European Journal of Medicinal Chemistry, 2022, 240: 114579.

◎Qian Xie, Yanni Shen, Jianhui Liang, Chao Zhang, Xianwu Ling, Liangxiao Gu, Yiling Wang, Yan Wang, Xiaoping Liu, Chun Hu. Design and synthesis of 1,3-diphenylpyrimidine-2,4(1H,3H)-dione derivatives as antitumor agents via elevating ROS production to induce apoptosis. New Journal of Chemistry, 2022, 46: 12278.

◎Chao Zhang, Jun-Jie Xiang, Jing Zhao, Yan-Li Meng, Fu-Rong Zhang, Zhe Jin, Pang-Chui Shaw, Xiao-Ping Liu, Chun Hu. Design, synthesis, and biological activity of a novel series of 2-ureidonicotinamide derivatives against influenza A virus. Current Medicinal Chemistry, 2022, 29: 4610-4627.

◎Li-Ping Jin, Chao Zhang, Qian Xie, Jing Xu, Lin Wang, Ling-Chen Yang, Er-Fang Huang, David Chi-Cheong Wan, Chun Hu. Design, synthesis and biological activity against estrogen receptor-dependent breast cancer of furo[1]benzofuran derivatives. Arabian Journal of Chemistry, 2022, 15: 104227.

◎Jing Zhao, Zhe Jin, Run Wang, Xin'geng Zhang, Yinmei Han, Chun Hu, Xiaoping Liu, Chuanming Zhang, Liping Jin. Design, synthesis and anticancer activity of 2-((pyridin-2-ylmethyl)thio)-1H-benzimidazole derivatives. Chinese Journal of Organic Chemistry, 2022, 42: 2172-2183.

◎Yanni Shen, Qian Xie, Yiling Wang, Jianhui Liang, Cuilu Jiang, Xiaoping Liu, Yan Wang, Chun Hu. Design, synthesis and anti-osteosarcoma activity study of novel pyrido[2,3-d]pyrimidine derivatives by inhibiting DKK1-Wnt/β-catenin pathway. Biorganic Chemistry, 2023, 141: 106848.

◎Jianfei Gao, Shunyi Li, Yulong He,  Yingxia Li, Heyao Wang, Erfang Wang, Chun Hu. Design, synthesis and biological evaluation of FABP4/5 inhibitors based on quinoline scaffold.  Chinese Journal of Organic Chemistry, 2023, 43: 636-645.

◎Shicheng Hou, Tai Li, Jiangqing Yan, Dong Cai, Yang Peng, Haibo Zhang, Feng Tong, Haiming Fan, Xiaoping Liu, Chun Hu. Design, synthesis and antibacterial activity of novel 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives. Heliyon, 2024, 10: e24589.

◎Tai Li, Jiawei Wang, Limiao Feng, Qi Zhou, Qian Xie, Yanni Shen, Rongxin Ji, Xiaoping Liu, Yan Wang, Chun Hu. Discovery of novel thiophene-3-carboxamide derivatives as potential VEGFR-2 inhibitors with anti-angiogenic properties. Biorganic Chemistry,  2024, 147: 107358.

◎Tao Li, Ying Zheng, Lin Guo, Yanping Xie, Yiling Wang, Ziyu Li, Shicheng Hou, Xiaoping Liu, Chun Hu. Stereoselective synthesis and mechanism of bicyclic iminosugars. Chemical Research in Chinese Universities, 2025, 41:  (online). https://doi.org/10.1007/s40242-025-4225-7.